What is the diagnostic testing for HIV-associated distal painful sensorimotor polyneuropathy?

Updated: Aug 08, 2019
  • Author: Florian P Thomas, MD, PhD, MA, MS; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Answer

Distal painful sensorimotor polyneuropathy is a diagnosis of exclusion. Skin punch biopsy for epidermal nerve fiber density is a valuable tool. [24] Scales have been developed to measure the degree of neuropathy. Total neuropathy score (TNS) uses the neurologic exam and nerve conductions studies. The brief peripheral neuropathy screen (BPNS) is based on lower extremity symptoms, ankle reflexes, and vibration sense. [14]  A modified TNS replaces nerve conduction testing with autonomic indices. [25]


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