What causes CNS cryptococcosis in HIV infection?

Updated: Jan 08, 2020
  • Author: Felicia J Gliksman, DO, MPH; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
  • Print


Cryptococcus neoformans is a round or oval yeast, 4-6 mm in diameter, surrounded by a 30-mm-thick capsule. Based on the polysaccharide wall serology, use of nutrients, and DNA sequence, it is subclassified into C neoformans neoformans and C neoformans gattii. Most HIV-associated cryptococcal infections are caused by Cryptococcusneoformans, serotype A (found worldwide), but occasionally Cryptococcus gattii is the cause (found in Australia, subtropical regions, and the Pacific Northwest).

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!