What is the role of brain biopsy in the workup of CNS toxoplasmosis in HIV infection?

Updated: Jul 11, 2017
  • Author: Gulshan Uppal, MD; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Indications for brain biopsy include either of the following:

  • Single mass lesion and negative serologic results

  • No response to 14 days of empiric therapy

Diagnostic yield of stereotactic biopsies increases with the number of specimens obtained.

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