Which clinical history findings are characteristic of spinal epidural abscess?

Updated: Jul 12, 2018
  • Author: J Stephen Huff, MD, FACEP; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Clinical presentation may be quite variable. The clinical triad of fever, back pain, and neurologic deficit is not present in most patients. [6, 8] Early presentations may be subtle, and atypical presentations are not unusual. A 4-phase sequential evolution has been described, with (1) localized spinal pain, (2) radicular pain and paresthesias, (3) muscular weakness, sensory loss, and sphincter dysfunction, and finally (4) paralysis. [1]

  • The virulence of the infecting organism and the mode of infection contribute to the tempo of this progression. Abscesses from hematogenous spread tend to progress rapidly, while abscesses from osteomyelitis or discitis may evolve over weeks or months with slow progression of symptoms.

  • Frequently the patient gives a history of back strain or mild injury.

  • An evident source of infection in skin or soft tissue may be found.

  • IV drug users are a high-risk group. Occurrences have been cited even in patients with a remote history of IV drug abuse. [7]

  • Cases are frequently reported in patients with diabetes mellitus, which is a risk factor in 50% of reported patients; alcoholism; and conditions involving chronic immunosuppression.

  • Hematogenous seeding of the epidural space with abscess formation may stem from intravenous lines, urinary catheters, or implantable devices. Direct inoculation of the epidural space may follow spinal surgery, epidural catheter placement, or epidural injections.

  • Symptoms may include the following:

    • Fever, present in only about one third of patients

    • Localized back pain in most patients, often the first symptom

    • Radiculopathy with radiating or lancinating pain, including chest or abdominal pain (At times this may simulate myocardial infarction or other causes of chest or abdominal pain.)

    • Spinal cord syndromes, typically involving paraparesis with prospective progression to paraplegia (Epidural abscesses at the level of the cauda equina cause symptoms consistent with cauda equina syndrome rather than a spinal cord syndrome.)

    • Central cord syndrome from epidural abscess has also been reported. [9]

    • Sphincter dysfunction, including incontinence or increased residual urine volumes

    • Headache and neck pain may be present, especially with cervical epidural abscesses. (Of course, these symptoms might also suggest meningitis.)


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