What is the role of PCR in the workup of meningococcal meningitis?

Updated: Jul 16, 2018
  • Author: Francisco de Assis Aquino Gondim, MD, PhD, MSc, FAAN; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

The polymerase chain reaction (PCR) [12] may be used to complement standard laboratory procedures for the diagnosis of meningococcal meningitis. [13] The IS1106 PCR is a rapid and sensitive test for confirmation of the diagnosis; its sensitivity is not affected by prior antibiotic treatment. [14] PCR of the nspA gene was also reported to be a fast diagnostic test. [15]


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