What is the incidence of herpes simplex encephalitis (HSE) in the US?

Updated: Jul 17, 2018
  • Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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In the United States, HSE is the most common nonepidemic encephalitis and the most common cause of sporadic lethal encephalitis. Incidence is 2 cases per million population per year. HSE may occur year-round. HSV-1 is ubiquitous, and HSV-2 is also common. International incidence is similar to that in the United States.

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