What is the prevalence of primary herpes simplex encephalitis (HSE) in children?

Updated: Jul 17, 2018
  • Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

In children, encephalitis often results from primary infection with HSV. Approximately 80% of children with HSE do not have a history of labial herpes. Perez de Diego, et al., note inborn errors or novel proteins may play a role in childhood susceptibility to HSE.


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