What are the persistent deficits of Haemophilus influenzae type b (Hib) meningitis?

Updated: Jul 09, 2018
  • Author: Prateek Lohia, MD, MHA; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Some sequelae of Hib meningitis are transient; others lead to chronic or even permanent problems. Despite adequate treatment of children with Hib meningitis, approximately 20-40% are left with persistent sequelae. Some studies report that deficits are present in more than 50% of survivors. Permanent deficits are more likely in patients whose diagnosis and treatment is delayed and in those who are treated with less effective antibiotics (eg, ones to which the pathogens are resistant). The general categories are as follows:

  • Seizures and epilepsy

  • Hearing loss

  • Other cranial nerve deficits

  • Ataxia

  • Hemiparesis

  • Cognitive and behavioral disturbances


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