Which lab testing and imaging studies should be performed in the diagnosis of Addison disease?

Updated: Mar 11, 2020
  • Author: George T Griffing, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Other tests performed in the diagnosis of Addison disease include the following:

  • Comprehensive metabolic panel
  • Complete blood cell (CBC) count
  • Thyroid-stimulating hormone (TSH) levels
  • Autoantibody testing: Thyroid and/or adrenal autoantibodies may be present
  • Prolactin testing: Modest hyperprolactinemia has been reported in cases of Addison disease and also in secondary adrenocortical insufficiency

Imaging studies include the following:

  • Chest radiograph:
  • Computed tomography (CT) scan: An abdominal CT scan may be normal but may show bilateral enlargement of the adrenal glands in patients with Addison disease because of tuberculosis (TB), fungal infections, adrenal hemorrhage, or infiltrating diseases involving the adrenal glands

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