What is the role of arterial blood gas (ABG) measurement in the workup of status epilepticus (SE)?

Updated: Feb 13, 2018
  • Author: Julie L Roth, MD; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Arterial blood gas (ABG) measurement may be useful to monitor oxygenation and ventilation efficacy and to discover any unexpected acid-base abnormalities. An episode of generalized seizures will typically result in a metabolic acidosis, but this should correct rapidly following seizure cessation as the lactate generated by vigorous muscle contractions is metabolized. Profound metabolic acidosis and continuing seizures might raise the possibility of isoniazid poisoning (see Isoniazid Toxicity in Emergency Medicine).

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