What is the role of lab tests in the workup of cerebral amyloid angiopathy (CAA)?

Updated: Dec 19, 2018
  • Author: Ravi S Menon, MD; Chief Editor: Helmi L Lutsep, MD  more...
  • Print
Answer

Answer

No specific laboratory findings are diagnostic of cerebral amyloid angiopathy (CAA). However, some patients may have cerebrospinal fluid (CSF) abnormalities; specifically, increased protein and decreased soluble β-amyloid or ApoE.

Genetic evaluation can be considered, especially in patients with a family history of CAA. In cases of CAA-related ICH, laboratory studies should rule out other possible etiologies.

With regard to electroencephalography, electroencephalograms (EEGs) may be diffusely abnormal, but they usually do not show evidence of seizure focus.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!