What are the neurologic signs and symptoms of cerebral amyloid angiopathy (CAA)?

Updated: Dec 19, 2018
  • Author: Ravi S Menon, MD; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Answer

Stereotyped transient neurologic events commonly consist of focal weakness, paresthesias, or numbness. In some cases, these events may be prodromes for larger hemorrhages.

The symptoms spread to contiguous body parts over 2-10 minutes, and they may involve areas in several vascular territories. These events are probably due to small, petechial cortical hemorrhages that lead to focal seizures. The rate of spread is akin to that seen in migraine; some have proposed that these episodes may represent spreading depression of neuronal activity. Some patients present with transient confusion or episodes of visual misperceptions.


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