What are the signs and symptoms of ICH in cerebral amyloid angiopathy (CAA)?

Updated: Dec 19, 2018
  • Author: Ravi S Menon, MD; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Answer

CAA most often comes to clinical attention because of ICH. Symptoms range from transient weakness to coma, depending on the size and location of the hemorrhage. Patients may have recurrent episodes.

The most common symptom at onset is headache (60-70% of patients), with the location of the pain varying in accordance with the location of the hematoma, as follows:

  • Frontal hematomas - Bifrontal headache pain

  • Parietal bleeds - Usually unilateral temple pain

  • Temporal hematomas - Ipsilateral eye and ear pain

  • Occipital bleeds - Ipsilateral eye pain

Vomiting (in 30-40% of patients) tends to occur early. Seizures occur at onset in 16-36% of patients. Seizures are most commonly partial, with symptoms determined by the location of the ICH. As many as half of the patients present in status epilepticus.


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