Which patient groups have the highest prevalence of cerebral amyloid angiopathy (CAA)?

Updated: Dec 19, 2018
  • Author: Ravi S Menon, MD; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Answer

Upon autopsy, CAA may be found more commonly in women than in men; however, the incidence of ICH is the same in women and men.

The severity of CAA is age related, and more than 50% of patients in the tenth decade of life have evidence of CAA. Increasing age and the presence of AD are the only identified risk factors for CAA. Sporadic CAA-related ICH occurs in patients aged 60 years or older.

Familial forms of CAA are associated with hemorrhage at younger ages, by the third or fourth decade in the Icelandic form and by the sixth decade among the Dutch kindreds. Hemorrhage occurs at the same age in men and women.


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