What is the efficacy of endovascular therapy for cerebral aneurysms?

Updated: Dec 06, 2018
  • Author: David S Liebeskind, MD, FAAN, FAHA, FANA; Chief Editor: Helmi L Lutsep, MD  more...
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A meta-analysis of relevant studies (including ISAT) found that endovascular coiling of cerebral aneurysms yields a better clinical outcome than clipping does, with the benefit greatest in patients with a good preoperative grade. [1, 2] The analysis also confirmed, however, that there is a greater risk of rebleeding with coiling, particularly for patients with a poor preoperative grade. Patient mortality at 1 year with coiling was not significantly different from 1-year mortality with clipping. [1, 2]

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