Which medications in the drug class Calcium channel blockers are used in the treatment of Fibromuscular Dysplasia?

Updated: Jul 27, 2018
  • Author: James A Wilson, MD, MSc, FRCPC; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Calcium channel blockers

These agents are used in cases of subarachnoid hemorrhage.

Nimodipine (Nimotop)

To improve neurologic impairments resulting from vasospasm after subarachnoid hemorrhage caused by a ruptured congenital intracranial aneurysm in patients who are in good neurologic condition postictus.

Studies show benefit on the severity of neurologic deficits caused by cerebral vasospasm after subarachnoid hemorrhage, but no evidence indicates that the drug either prevents or relieves spasm of the cerebral arteries. Actual mechanism of action unknown, and a neuroprotective effect is suggested.

Therapy should start within 96 h of the subarachnoid hemorrhage. If capsule cannot be swallowed because patient is undergoing surgery or unconscious, a hole can be made at both ends of the capsule with an 18-gauge needle and the contents extracted into a syringe and emptied into the patient's in situ nasogastric tube and flush with 30-mL isotonic saline.


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