What is included in the workup of fibromuscular dysplasia (FMD)?

Updated: Jul 27, 2018
  • Author: James A Wilson, MD, MSc, FRCPC; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Routine laboratory investigations are usually nonproductive but may show renal impairment.

Imaging considerations include the following:

  • A history of stroke or transient ischemic attack (TIA) in a young individual or a subarachnoid hemorrhage in a person of any age should prompt cerebrovascular imaging; such imaging is also indicated for any individual known to have FMD

  • Conventional angiography is standard for detecting FMD and its associated vascular lesions

  • Conventional cerebrovascular ultrasonography is unlikely to depict the carotid lesions of FMD

  • The sensitivity and specificity of computed tomography (angiography (CTA), time-of-flight (TOF) magnetic resonance angiography (MRA), or contrast-enhanced MRA (CE MRA) in this setting remain to be established

  • Conventional CT and MRI may be useful in finding ischemic strokes caused by arterial dissection or the FMD lesions themselves, as well as for detecting subarachnoid hemorrhage


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