What is fibromuscular dysplasia (FMD)?

Updated: Jul 27, 2018
  • Author: James A Wilson, MD, MSc, FRCPC; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Fibromuscular dysplasia (FMD) is an angiopathy that affects medium-sized arteries predominantly in young women of childbearing age. Among patients with identified FMD, renal involvement occurs in 60-75%, cerebrovascular involvement in 25-30%, visceral involvement in 9%, and arteries of the limbs in about 5%. [1, 2] FMD occurs in most other medium-to-large arteries as well, including the coronary arteries, [3] the pulmonary arteries, [4] and the aorta. [5] See the image below.

Angiogram of the descending aorta demonstrates the Angiogram of the descending aorta demonstrates the stenoses of FMD in the renal arteries bilaterally.

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