Which medications in the drug class Antihypertensive agents are used in the treatment of Basilar Artery Thrombosis?

Updated: Jan 11, 2019
  • Author: Salvador Cruz-Flores, MD, MPH, FAHA, FCCM, FAAN, FACP, FANA; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Antihypertensive agents

These agents control severe hypertension. They are recommended for patients considered candidates for thrombolytic therapy who have a systolic blood pressure of greater than 185mm Hg and/or a diastolic blood pressure of greater than 110mm Hg.

Nicardipine (Cardene)

Nicardipine relaxes coronary smooth muscle and produces coronary vasodilation, which, in turn, improves myocardial oxygen delivery and reduces myocardial oxygen consumption.

Labetalol

Labetalol blocks beta1-, alpha-, and beta2-adrenergic receptor sites, decreasing blood pressure.

Nitroprusside sodium (Nitropress)

Nitroprusside sodium produces vasodilation and increases inotropic activity of the heart. At higher dosages, it may exacerbate myocardial ischemia by increasing the heart rate.

Enalapril (Vasotec, Epaned)

Enalapril is a competitive inhibitor of angiotensin-converting enzyme (ACE). It reduces angiotensin II levels, decreasing aldosterone secretion.


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