When is screening for procoagulant conditions included in the workup of basilar artery thrombosis?

Updated: Jan 11, 2019
  • Author: Salvador Cruz-Flores, MD, MPH, FAHA, FCCM, FAAN, FACP, FANA; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

Young patients (< 45 y) or patients with no evidence of atherosclerosis should be investigated for the presence of procoagulant conditions. However, these tests may need to be repeated several weeks after the acute event to establish whether the abnormality was a response to the acute event or an actual abnormality. These patients are typically screened for the following procoagulant conditions:

  • Protein C, protein S, and antithrombin III deficiencies, especially if the patients has evidence of paradoxical embolism, because these disorders have a stronger association with venous rather than arterial thrombosis

  • Lupus anticoagulant and anticardiolipin antibodies

  • Homocysteine level


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