What is the efficacy of surgical resection for the treatment of brain metastasis?

Updated: Aug 01, 2018
  • Author: Victor Tse, MD, PhD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

Surgical resection is considered standard care for solitary metastases larger than 3 cm and in noneloquent areas of the brain.

Surgical resection is superior to radiosurgery, with a median survival nearly twice that of radiosurgery. About 13% of surgically treated patients have local recurrence, whereas 39% of patients treated with radiosurgery have local progression of disease.

Cho and Auchter reported that combined therapies (eg, resection plus radiosurgery or radiosurgery plus WBRT) yield outcomes better than those of WBRT alone. [20, 21]

Read more in Stereotactic Radiosurgery in the Management of Brain Metastasis.


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