How does the origin of a single brain metastasis differ from multiple metastases?

Updated: Aug 01, 2018
  • Author: Victor Tse, MD, PhD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Metastatic disease from the breast, thyroid, renal cells, and colon are more commonly found as a single metastatic lesion, whereas metastatic disease from lung cancer and melanoma are more commonly found to be multiple lesions. Testicular tumor is a uncommon cancer and yet it more frequently metastasizes to the brain as compared with lung cancer.

Patients with brain metastasis at the same time of having systemic cancer (synchronous metastasis) tend to do worse as compared with patients with metachronous metastatic disease.

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