What is the incidence of primary central nervous system lymphoma (PCNSL)?

Updated: Jan 19, 2018
  • Author: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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PCNSL incidence has risen steadily since the end of the twentieth century. Incidence in immunocompetent patients is approximately 51 cases per 10,000,000 per year.

PCNSL has been reported in 6-20% of patients infected with HIV, and the incidence is expected to rise as patients with low CD4+ counts survive longer.

Similar trends toward rising frequency of diagnosis of PCNSL are reported internationally.

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