Which Trace (D) values on MRI suggest multiple system atrophy (MSA)?

Updated: Oct 17, 2018
  • Author: André Diedrich, MD, PhD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

A study using diffusion-weighted MRI showed that patients with MSA with predominant parkinsonism (MSA-P) had significantly higher Trace (D) values in the entire and anterior putamen, whereas patients with MSA with cerebellar features (MSA-C) had significantly higher Trace (D) values in the cerebellum and middle cerebellar peduncle. Furthermore, increased disease duration correlated significantly with increased Trace (D) values in the pons of patients with MSA-P and in the cerebellum and middle cerebellar peduncle of patients with MSA-C. [35]


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