What is the role of imaging studies in the workup of autonomic failure syndrome?

Updated: Oct 21, 2018
  • Author: Mohini Gurme, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

See the list below:

  • Brain MRI may be useful, particularly in cases of centrally mediated dysautonomia.

  • In MSA, brainstem or cerebellar atrophy may be seen, with T2 hyperintensity of the pons (the hot-crossed bun sign); these findings differentiate MSA from the other conditions of primary autonomic dysfunction. [4]

  • No imaging abnormalities are expected in pure autonomic failure, autoimmune autonomic neuropathy, or postural orthostatic tachycardia syndrome.


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