What are the symptoms of pure autonomic failure (PAF)?

Updated: Oct 21, 2018
  • Author: Mohini Gurme, MD; Chief Editor: Selim R Benbadis, MD  more...
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More specifically, symptoms of PAF include the following:

  • Orthostatic hypotension: With an inappropriate lack of compensatory increase in heart rate with standing

  • Gastroparesis: Associated with nausea or constipation

  • Urinary retention: May cause bladder distention

  • Decreased sweating: Manifesting as heat or exercise intolerance

  • Ophthalmologic manifestations: Including ptosis, anisocoria, Horner syndrome, and tonic pupils

  • Failure of either erection or ejaculation

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