What is the incidence of progressive supranuclear palsy (PSP)?

Updated: Sep 24, 2018
  • Author: Stephen M Bloomfield, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Answer

In the Olmsted County Database, the average annual incidence for individuals aged 50-99 was 5.3 per 100,000 population. Overall, estimates suggest that PSP is about as common as motor neuron disease. A high incidence of PSP has been reported in the French Antilles, approaching 14 cases per 100,000 population in Guadeloupe. This high incidence might be related to environmental neurotoxins found in herbal teas and fruits that are commonly consumed there. PSP with tau doublets was found in all 3 cases of probable PSP in which autopsy was performed.


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