What is tardive dystonia?

Updated: Oct 17, 2018
  • Author: James Robert Brasic, MD, MPH; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Answer

Tardive dystonia occurs in 1-2% of individuals during long-term treatment with dopamine antagonists. It must be differentiated from acute dystonia, which occurs in the first days of neuroleptic treatment or after an increase in the dose. Tardive dystonia presents as fixed posturing of the face and neck (eg, anterocollis, retrocollis, torticollis), extremities, and trunk. It may be either localized, involving 1 or more body parts, or generalized. Unlike TD, tardive dystonia may improve with anticholinergic medication.

Unlike TD, torsion dystonia is an inherited disorder with childhood onset that typically occurs in people of Ashkenazi Jewish descent.


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