What is the mortality and morbidity associated with olivopontocerebellar atrophy (OPCA)?

Updated: Dec 17, 2018
  • Author: Sombat Muengtaweepongsa, MD, MSc; Chief Editor: Selim R Benbadis, MD  more...
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Answer

The OPCAs are progressive neurodegenerative disorders that have no definitive treatment. Eventually, many patients become wheelchair bound. Severe dysarthria, anarthria, and dysphagia are not uncommon as the disease progresses.

  • Morbidity increases significantly, including falls and aspiration pneumonia.

  • Enteral feeding becomes necessary for many patients.

  • Death commonly results from aspiration pneumonia.

  • The duration of familial OPCA is approximately 15 years. The duration of sporadic OPCA is approximately 6 years.


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