What is the role of harmane, a heterocyclic amine (HCA), in the etiology of essential tremor?

Updated: Oct 22, 2018
  • Author: Deborah A Burke, MD; Chief Editor: Selim R Benbadis, MD  more...
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Harmane, a heterocyclic amine (HCA), is a potent tremor-producing neurotoxin. It is often found in the human diet. Blood concentrations have been found to be elevated in patients with essential tremor as compared with controls. [11] The most likely etiology appears to be alterations in metabolism rather than increased dietary intake.

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