Which lab tests are performed in the workup of cerebrovascular disease during pregnancy?

Updated: Aug 20, 2019
  • Author: Carmel Armon, MD, MSc, MHS; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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The choice of laboratory studies depends on the mechanism of the stroke and on whether the arterial or the venous system is involved. Studies may include the following:

  • Hemoglobin electrophoresis

  • Fasting homocysteine level determination

  • Cholesterol panel

  • Anticardiolipin or antiphospholipid antibody tests

  • Thrombin time determination for dysfibrinogenemia and for factor V Leiden

  • Prothrombin G20210A mutation tests

  • Protein C or S tests – Note that protein S activity is decreased during pregnancy; if possible, the protein study should be performed 6-8 weeks after delivery

  • Antithrombin III assays

Other studies may be indicated to investigate for SLE, other causes of vasculitis, and other systemic diseases.

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