What is the role of cyclophosphamide in the treatment of multiple sclerosis during pregnancy?

Updated: Aug 20, 2019
  • Author: Carmel Armon, MD, MSc, MHS; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Answer

Answer

Cyclophosphamide is teratogenic in animals, but whether it is also teratogenic in humans has not been clearly determined. [57] Nevertheless, it is a category D agent and therefore should be avoided in pregnant patients.


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