What is the role of mitoxantrone in the treatment of multiple sclerosis during pregnancy?

Updated: Aug 20, 2019
  • Author: Carmel Armon, MD, MSc, MHS; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
  • Print


Mitoxantrone has been associated with low birth weight and abnormal fetal kidney development in animal studies. Rats treated with mitoxantrone had an increased incidence of preterm labor. [53] Because of its known risk in pregnancy, mitoxantrone should not be used in pregnant patients.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!