Which medications used in the treatment of neurologic disease should be discontinued during pregnancy?

Updated: Nov 08, 2018
  • Author: Carmel Armon, MD, MSc, MHS; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Answer

Answer

If the woman is already pregnant and did not consult her physician in advance, she must alert her obstetrician and neurologist as soon as possible. Her physicians should review her current medications for their teratogenic potential, and drugs that pose a significant teratogenic risk should be discontinued if possible.

It is important, however, that medications be discontinued only when doing so makes good clinical sense for the mother, not solely because they may be associated with congenital anomalies. For example, if antiseizure medications are stopped prematurely, seizure activity may increase during the pregnancy and eventually expose the fetus to several medications at doses higher than those originally used to control the condition.


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