Which medications in the drug class Corticosteroids are used in the treatment of Cauda Equina and Conus Medullaris Syndromes?

Updated: Jun 14, 2018
  • Author: Segun Toyin Dawodu, JD, MD, MS, MBA, LLM, FAAPMR, FAANEM; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Answer

Corticosteroids

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Methylprednisolone (DepoMedrol, Medrol, Medrol Dosepak)

This agent decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability. This prevents further worsening of injury.

Treatment must be started within 8 h of injury; treatment apparently has no benefit if started later than 8 h after injury. Late treatment may have detrimental effects.


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