What is the role of EMG and nerve conduction studies in the workup of neurosarcoidosis?

Updated: Nov 13, 2018
  • Author: Gabriel Bucurescu, MD, MS; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Answer

Electromyography/nerve conduction studies (EMG/NCS) can be used to confirm neuropathy. Findings include slowing of motor nerve conduction velocities, as well as abnormal sensory nerve conduction consisting of absent potentials, reduced amplitude, and mild slowing. Mixed compound nerve action potentials may be seen as well.

The most characteristic electrodiagnostic finding is mononeuropathy multiplex, showing axonal degeneration and segmental demyelination. In cases of myopathy, the EMG shows myopathic potentials. With treatment and clinical improvement, motor, sensory, and mixed nerve conduction tend to improve.


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