What are presentations of cranial nerve mononeuropathy, in relation to neurosarcoidosis?

Updated: Nov 13, 2018
  • Author: Gabriel Bucurescu, MD, MS; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Answer

The facial nerve is the most commonly affected cranial nerve in neurosarcoidosis. Either unilateral or bilateral involvement may occur.

Heerfordt syndrome is a rare manifestation characterized by fever, uveitis, swelling of the parotid gland, and facial nerve palsy. It represents a type of neurosarcoidosis. The lesion site has been controversial, but direct nerve compression by parotid gland swelling or by a lesion within the facial canal has been assumed, in light of observations of accompanying taste disturbance.

A rare case of gingival sarcoidosis has been described in a patient with cranial nerve involvement. [16]


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