What is the role of MRI in the workup of acute disseminated encephalomyelitis (ADEM)?

Updated: Nov 08, 2018
  • Author: J Nicholas Brenton, MD; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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T2-weighted and fluid attenuated inversion recovery (FLAIR), proton-density, or echo-planar trace diffusion MRI techniques disclose characteristic high-signal lesions in virtually all cases of ADEM. [47] T2/FLAIR images are particularly important in the evaluation of young individuals presenting with inflammatory CNS demyelinative illnesses that may be ADEM or MS. [11] Apparent diffusion coefficient maps show high-signal changes consistent with vasogenic edema.


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