What are the main differential diagnoses for multiple sclerosis (MS)?

Updated: Oct 08, 2019
  • Author: Christopher Luzzio, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
  • Print
Answer

The main differential diagnoses for MS include, but are not limited to, the following:

  • Spinal cord neoplasms (eg, astrocytomas, ependymomas)

  • Acute disseminated encephalomyelitis (ADEM)

  • Schilder disease

  • Baló concentric sclerosis

  • Sarcoidosis

  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

  • Transverse myelitis

  • Infarction of the spinal cord

  • Vasculitis

  • Radiation myelitis

  • Arteriovenous fistula

  • Progressive multifocal leukoencephalitis

  • Subacute combined degeneration of the spinal cord (vitamin B12 deficiency)

  • Small-vessel ischemic disease (affecting the brain primarily, and caused by diseases with vascular risk factors, such as diabetes, hypertension, hyperlipidemia, old age)


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!