What is the prevalence of multiple sclerosis (MS) in the US, and which patient populations are most commonly affected?

Updated: Oct 08, 2019
  • Author: Christopher Luzzio, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Prevalence estimates for MS in the United States vary from 58 to 95 per 100,000 population. [49] According to the National Multiple Sclerosis Society, 400,000 individuals in the United States are affected by MS. [50] Misdiagnosis is common, however.

As is true of autoimmune diseases in general, MS is more common in women. The female-to-male ratio of MS incidence has increased since the mid-20th century, from an estimated 1.4 in 1955 to 2.3 in 2000. [38] MS is usually diagnosed in persons aged 15–45 years; however, it can occur in persons of any age. The average age at diagnosis is 29 years in women and 31 years in men.

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