What are the different types of multiple sclerosis (MS)?

Updated: Oct 08, 2019
  • Author: Christopher Luzzio, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Answer

MS is divided into the following categories, principally on the basis of clinical criteria, including the frequency of clinical relapses, time to disease progression, and lesion development on MRI: [1, 2, 3, 4]

  • Relapsing-remitting MS (RRMS): Approximately 85% of cases

  • Secondary progressive MS (SPMS)

  • Primary progressive MS (PPMS)

  • Progressive-relapsing MS (PRMS)

The following 2 subgroups are sometimes included in RRMS:

  • Clinically isolated syndrome (CIS): A single episode of neurologic symptoms

  • Benign MS: MS with almost complete remission between relapses and little if any accumulation of physical disability over time

See Workup for more detail.


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