Which medications in the drug class Corticosteroids are used in the treatment of Complex Regional Pain Syndromes?

Updated: Jun 20, 2018
  • Author: Gaurav Gupta, MD; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Answer

Corticosteroids

These agents have anti-inflammatory properties. They can cause profound and varied metabolic effects and modify the body's immune response to diverse stimuli.

Methylprednisolone (Adlone, Medrol, Solu-Medrol)

Should be given in the acute phase of CRPS type I. May decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. After 4 wk of treatment, symptoms and signs should be decreased by 65%.

Prednisone (Sterapred)

Can be used in early phase of CRPS. Not useful in late stages. May decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.


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