Which techniques are used to block sympathetic activity in the treatment of complex regional pain syndrome (CRPS)?

Updated: Jun 20, 2018
  • Author: Gaurav Gupta, MD; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Therapeutic techniques used to block sympathetic activity include the following:

  • Injections of local anesthetic around the sympathetic paravertebral ganglia that project to the affected body part (sympathetic ganglion blocks).

  • Regional IV applications of guanethidine, bretylium, or reserpine (all of which deplete norepinephrine in the postganglionic axon) to an isolated extremity blocked with a tourniquet (intravenous regional sympatholysis).

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