What is the role of muscle biopsy in the evaluation of complex regional pain syndrome (CRPS)?

Updated: Jun 20, 2018
  • Author: Gaurav Gupta, MD; Chief Editor: Stephen A Berman, MD, PhD, MBA  more...
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Answer

Skeletal muscles in the affected extremities demonstrate (1) a decrease in type 1 fibers, (2) an increase in lipofuscin pigment, (3) atrophic fibers with a slight angular appearance, and (4) severely thickened basal membrane layers in the capillaries.


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