Which histologic findings are characteristics of trigeminal neuralgia (TN)?

Updated: Jul 11, 2019
  • Author: Manish K Singh, MD; Chief Editor: Robert A Egan, MD  more...
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Although not a diagnostic test, histology reveals focal demyelination as the ultimate lesion in both secondary and idiopathic cases of trigeminal neuralgia. In some instances (eg, tumor) of secondary cases of trigeminal neuralgia, the underlying lesion can be assessed by histology. The most frequent anatomic location is the root entry zone (REZ).

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