What is the role of lidocaine in the performance of therapeutic injections for pain management?

Updated: Jun 19, 2018
  • Author: Anthony H Wheeler, MD; Chief Editor: Meda Raghavendra (Raghu), MD  more...
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Lidocaine is a widely used LA because of its rapid onset, potency, and tissue penetration. Within this group bupivacaine is also a popular and frequently used LA for peripheral nerve block and epidural or spinal anesthesia. Commercially available concentrations of this drug range from 0.125-0.75%. Altering the concentration of bupivacaine can elicit a separate sensory or motor neural blockade, ie, lower concentrations primarily induce a sensory block, whereas higher concentrations cause motor blockade. Bupivacaine alters myocardial conduction more dramatically than lidocaine; therefore, the need for cardiorespiratory monitoring during the use of LAs should be emphasized.

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