What is the role of lidocaine 4% ophthalmic drops in the treatment of postherpetic neuralgia (PHN)?

Updated: Mar 06, 2018
  • Author: W Alvin McElveen, MD; Chief Editor: Robert A Egan, MD  more...
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Answer

In a small study by Kanai et al, lidocaine 4% ophthalmic drops were administered to 24 patients with ophthalmic postherpetic neuralgia in a crossover manner. A significant reduction in eye and forehead pain was observed in patients who received the lidocaine ophthalmic drops. Analgesic onset was noted via a visual analog scale within 15 minutes after administration and persisted for a median of 36 hours (range, 8-96 h). [13]


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