What is migralepsy?

Updated: Oct 16, 2019
  • Author: Rima M Dafer, MD, MPH, FAHA; Chief Editor: Helmi L Lutsep, MD  more...
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Migraine and epilepsy are highly comorbid conditions, probably sharing the same pathophysiology, but the nature of their association is unclear. Migralepsy (migraine-triggered seizures) is the term used when a seizure occurs during or within 1 hour of a typical migraine aura attack. [65]

Reversible brain MRI abnormalities have been reported in a patient with migraine-triggered seizure, possibly as a consequence of supratentorial focal cerebral edema. [66, 67] Normal interictal findings are usually noted on electroencephalography (EEG), though various abnormalities, mainly diffuse slowing, have been reported in migraineurs.

Antiepileptic agents are the drugs of choice because of their dual benefit in migraine prevention and seizure control.

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