Which medications in the drug class Serotonin 5-HT1F Agonists (Ditans) are used in the treatment of Migraine Headache?

Updated: Oct 21, 2019
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Helmi L Lutsep, MD  more...
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Serotonin 5-HT1F Agonists (Ditans)

Serotonin 5-HT1F receptor agonists (ie, ditans) do not elicit a vasoconstrictive effect, whereas triptans cause vasoconstriction via agonistic action at 5-HT1B/1D receptors. Because of this ditans may be used for acute migraine attacks in patients with cardiovascular risks.

Lasmiditan (Reyvow)

Serotonin 5-HT1F receptor agonist indicated to treat acute migraine with or without aura.

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