When is lumbar puncture (LP) indicated in the evaluation of migraine headache?

Updated: Oct 21, 2019
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Helmi L Lutsep, MD  more...
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Indications for LP include the following:

  • First or worst headache of a patient's life

  • Severe, rapid-onset, recurrent headache

  • Progressive headache

  • Unresponsive, chronic, intractable headache

Neuroimaging (CT or MRI scan) should precede LP to rule out a mass lesion and/or increased intracranial pressure.

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